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Claude Sonnet 4.5 is a general-purpose model for coding and knowledge work from Anthropic. Call claude-sonnet-4-5-20250929 through MixRoute’s Anthropic-compatible Messages API; the OpenAI-compatible Chat Completions API is also supported.
Anthropic has deprecated Claude Sonnet 4.5 and scheduled its retirement from the Claude API for November 30, 2026. This is the Anthropic-operated API schedule, not a confirmed MixRoute removal date; availability through MixRoute depends on its upstream channels. Plan new integrations and migrations around Claude Sonnet 5.5.

Key capabilities

  • Messages API - Native Anthropic request and response format
  • OpenAI-compatible - Also works through Chat Completions
  • Streaming - Incremental output through SSE
  • System prompts - Top-level system instructions
  • Tool use - Supports Anthropic tool definitions

Quick example

Messages API

OpenAI-compatible API

Parameters

Messages API

OpenAI-compatible API